BestCurvFit - Curve-fitting Enzyme Kinetic Models to Data
 


Purchase BestCurvFit - New Version 7.7

BestCurvFit is one of the best choices to curve-fit kinetic models to data for scientific research. With just one-click of the mouse, BestCurvFit simplifies curve fitting your data to mathematical models. Select an equation from an internal library of 46 models or enter your own function, and BestCurvFit does the rest by fitting the curve to your data set, displays the statistical results and function parameters, draws the curve on the graph, and plots the residuals.

New and Improved Version 7.7 (March 27, 2021)
New and improved BestCurvFit revised with more robust nonlinear regression optimization analyses of functions that executes Hooke and Reeves, Simplex, Random Search, Quadratic programming, Variable metric, and Marquardt routines in tandem. Also, there are no limits or number of uses once the software is registered and activated. Improved graphics display of plots and statistical error analyses.

BestCurvFIt also includes statistic tests for the residuals plot. These tests include (1) Distribution-free Runs statistic test of the randomness of residuals, (2) F-test statistic to determines if the mean of the residuals is significantly different than zero, (3) Durbin-Watson statistic test of residuals to determine if a serial correlation exists, (4) Kolmogorov-Smirnov non-parametric, distribution-free, statistic test of residuals to determine whether positive and negative residuals come from the same distribution, and (5) Hotelling's T-squared distribution (T²) multivariate statistic used to measure dissimilarity for outlier detection in the data set.


Nonlinear regression curve-fitting software at an affordable price.

BestCurvFit is one of the best choices to curve-fit kinetic models to data for scientific research. With just one-click of the mouse, BestCurvFit simplifies curve fitting your data to mathematical models. Select an equation and BestCurvFit does the rest by fitting the curve to your data set, displays the statistical results and function parameters, draws the curve on the graph, and plots the residuals. BestCurvfit also includes an internal library of 46 mathematical models for analyzing enzyme kinetics and an ODE (Ordinary Differential Equation) solver for displaying systems of enzyme kinetic ODE's (Michaelis-Menten, Competitive Inhibition, Slow-binding Inhibition, Covalent binding inhibition, Suicide substrate model, and Drug/Inhibitor Receptor binding). In addition, a new ODE solver for the General Modifier Model of Botts-Morales has been added.

BestCurvFit includes an internal library of 46 mathematical models for analyzing enzyme kinetics. The library also includes models for evaluating inhibitors in the presence of substrate inhibition using Baici's Hyperbolic Substrate Inhibition equations and tight binding models. Also included is an ODE Solver for simulating seven enzyme kinetic systems (Michaelis-Menten, Competitive inhibition, Slow-binding inhibition, Covalent-binding inhibition, Suicide substrate, Drug-receptor inhibition, and the General Modifier Model of Botts-Morales).
BestCurvFit for MS Windows v7-10 (March 27, 2021)
BestCurvFit for MS Windows v7-10 (March 27, 2021)

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Download the latest version of BestCurvFit - It's robust and accurate!

Download the software zip file and then run BestCurvFit.exe to obtain the registration code to unlock the software on your computer. Purchase it using PayPal and email the registration code to us at DrFrank88@gmail.com No Windows installation is required. The zip file also contains 46 data file examples of the BestCurvFit model library.

Note: The BestCurvFit.lic and BestCurvFit.ini files must reside in the same folder as BestCurvFit.exe. A text editor (e.g., Notepad) must be used to create and save all data files. Do not use a word processor (e.g., MS Word) to create name.dat data files.


Download and unZip the file in a folder (e.g., C:\MyBestCurvFit\) on a computer you choose to license the software, and then run BestCurvFit.exe to retrieve the "Registration Code". The lack of formal Windows installation is intentional, as it allows installation without administrative privileges (no dynamic link libraries (DLL) are used). After you've paid for the software using PayPal, email us the Registration Code at drfrank88@gmail.com and we'll send you the Activation Code to enter and fully activate the software. Once activated, do not delete or modify the ini or lic files contained therein as they are required to execute and run the software. We suggest that you make backup copies of both the BestCurvFit.lic and BestCurvFit.ini files for future reference. BestCurvFit is copy-protected to run on one MS Windows 32 or 64-bit computer.
Note: When double-clicking to start BestCurvFit.exe, MS Windows Defender may consider this a risk and request if you trust the software. BestCurvFit has already been scanned by Windows Defender prior to uploading it to the website and no detectable threats were found. Therefore, to use BestCurvFit , select "More info" and then "Run anyway".

BestCurvFit.zip

File size: 1.09 MB

Download BestCurvFit ZIP file to your computer and unzip the file in a folder on your computer.

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BestCurvFit_Manual(rev2.3).pdf

File size: 4.24 MB

Free Curve-fitting and modeling guide to BestCurvFit v2.1.

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EZ-2x2_Calc.zip

File size: 380.44 KB

Free 2c2 Contingency Table Software

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Note: If your Chrome or Firefox browser flags the downloaded zip file with a cautionary warning, you have the option of selecting "keep" or "run anyway" to continue the download process or use MS Explorer instead. The BestCurvFit.zip file was scanned with Microsoft Windows Defender and shown not to have any detectable threats. The BestCurvFit software does not send any information back to us or anyone else. It is a standalone executable file (no DLL files) and does not required MS Windows installation.